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1

SPIE Proceedings [SPIE SPIE Advanced Lithography - San Jose, California (Sunday 12 February 2012)] Advances in Resist Materials and Processing Technology XXIX - Comparison of directed self-assembly integrations

Somervell, Mark, Gronheid, Roel, Hooge, Joshua, Nafus, Kathleen, Rincon Delgadillo, Paulina, Thode, Chris, Younkin, Todd, Matsunaga, Koichi, Rathsack, Ben, Scheer, Steven, Nealey, Paul, Somervell, Mar

Year:

2012

Language:

english

File:

PDF, 2.17 MB

english, 2012

2

Plasma β-Amyloid Peptide, Transforming Growth Factor-β1, and Risk for Cerebral Amyloid Angiopathy

STEVEN M. GREENBERG, HYUN-SOON CHO, HEATHER C. O'DONNELL, JONATHAN ROSAND, ALAN Z. SEGAL, LINDA H. YOUNKIN, STEVEN G. YOUNKIN, G. WILLIAM REBECK

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 206 KB

english, 2000

3

Detection of soluble forms of the β-amyloid precursor protein in human plasma

Marcia B. Podlisny, Andrew L. Mammen, Michael G. Schlossmacher, Mark R. Palmert, Steven G. Younkin, Dennis J. Selkoe

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 1.14 MB

english, 1990

4

Association of Low Plasma Aβ42/Aβ40 Ratios With Increased Imminent Risk for Mild Cognitive Impairment and Alzheimer Disease

Graff-Radford, Neill R., Crook, Julia E., Lucas, John, Boeve, Bradley F., Knopman, David S., Ivnik, Robert J., Smith, Glenn E., Younkin, Linda H., Petersen, Ronald C., Younkin, Steven G.

Journal:

Archives of Neurology

Year:

2007

Language:

english

File:

PDF, 225 KB

english, 2007

5

Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease

Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H.

Journal:

Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 195 KB

english, 2002

6

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

Westerman, Marcus A., Cooper-Blacketer, Deirdre, Mariash, Ami, Kotilinek, Linda, Kawarabayashi, Takeshi, Younkin, Linda H., Carlson, George A., Younkin, Steven G., Ashe, Karen H.

Journal:

Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 359 KB

english, 2002

7

Twofold overexpression of human ?-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury

Murai, Hisayuki, Pierce, Jean E.S., Raghupathi, Ramesh, Smith, Douglas H., Saatman, Kathryn E., Trojanowski, John Q., Lee, Virginia M.-Y., Loring, Jeanne F., Eckman, Chris, Younkin, Steven, McIntosh,

Journal:

The Journal of Comparative Neurology

Year:

1998

Language:

english

File:

PDF, 270 KB

english, 1998

8

Differences in the Aβ40/Aβ42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype

Anne M. Fagan, Linda H. Younkin, John C. Morris, John D. Fryer, Thomas G. Cole, Steven G. Younkin, David M. Holtzman

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 1.62 MB

english, 2000

9

Amyloid β protein levels in cerebrospinal fluid are elevated in early-onset Alzheimer's disease

Tamiko Nakamura, Dr. Mikio Shoji, Yasuo Harigaya, Mitsunori Watanabe, Kenji Hosoda, Tobun T. Cheung, Lillian M. Shaffer, Todd E. Golde, Linda H. Younkin, Steven G. Younkin, Shunsaku Hirai

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 808 KB

english, 1994

10

Evidence that Aβ42 is the real culprit in alzheimer's disease

Steven G. Younkin

Journal:

Annals of Neurology

Year:

1995

Language:

english

File:

PDF, 232 KB

english, 1995

11

Heritability of plasma amyloid β in typical late-onset Alzheimer’s disease pedigrees

Nilufer Ertekin-Taner, Neill Graff-Radford, Linda H. Younkin, Christopher Eckman, Jennifer Adamson, Daniel J. Schaid, John Blangero, Michael Hutton, Steven G. Younkin

Journal:

Genetic Epidemiology

Year:

2001

Language:

english

File:

PDF, 48 KB

english, 2001

12

Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Aβ42 levels and risk for Alzheimer disease

Nilüfer Ertekin-Taner, Mariet Allen, Daniel Fadale, Leah Scanlin, Linda Younkin, Ronald C. Petersen, Neill Graff-Radford, Steven G. Younkin

Journal:

Year:

2004

Language:

english

File:

PDF, 175 KB

english, 2004

13

Analysis of in Vivo-Derived Amyloid-β Polypeptides by On-Line Two-Dimensional Chromatography-Mass Spectrometry

Nigel J. Clarke, Frank W. Crow, Steven Younkin, Stephen Naylor

Journal:

Analytical Biochemistry

Year:

2001

Language:

english

File:

PDF, 113 KB

english, 2001

14

Antisense-Induced Reduction of Presenilin 1 Expression Selectively Increases the Production of Amyloid β42 in Transfected Cells

Lawrence M. Refolo, Chris Eckman, Christian-Mihail Prada, Debora Yager, Kumar Sambamurti, Nitin Mehta, John Hardy, Steven G. Younkin

Journal:

Journal of Neurochemistry

Year:

1999

Language:

english

File:

PDF, 188 KB

english, 1999

15

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

Karrie E Grear, I-Fang Ling, James F Simpson, Jennifer L Furman, Christopher R Simmons, Shawn L Peterson, Frederick A Schmitt, William R Markesbery, Qiang Liu, Julia E Crook, Steven G Younkin, Guojun

Journal:

Molecular Neurodegeneration

Year:

2009

Language:

english

File:

PDF, 678 KB

english, 2009

16

Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease

Christopher R Simmons, Fanggeng Zou, Steven G Younkin, Steven Estus

Journal:

Molecular Neurodegeneration

Year:

2011

Language:

english

File:

PDF, 922 KB

english, 2011

17

Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 andHMGCRsplicing in disease risk

Christopher R Simmons, Fanggeng Zou, Steven G Younkin, Steven Estus

Journal:

Molecular Neurodegeneration

Year:

2011

Language:

english

File:

PDF, 1.37 MB

english, 2011

18

Brain Aβ amyloidosis in APPsw mice induces accumulation of presenilin-1 and tau

Yasushi Tomidokoro, Yasuo Harigaya, Etsuro Matsubara, Masaki Ikeda, Takeshi Kawarabayashi, Tomoaki Shirao, Koichi Ishiguro, Koichi Okamoto, Steven G. Younkin, Mikio Shoji

Journal:

The Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 369 KB

english, 2001

19

Using peptide nucleic acids as gene-expression modifiers to reduce β-amyloid levels

Beth M. McMahon, Jennifer Stewart, Abdul Fauq, Steven Younkin, Linda Younkin, Elliott Richelson

Journal:

Journal of Molecular Neuroscience

Year:

2002

Language:

english

File:

PDF, 224 KB

english, 2002

20

Mayo and the mouse

Younkin, Steven G., Stoddard, Susan

Journal:

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

21

10.1038/5715

Iadecola, Costantino, Zhang, Fangyi, Niwa, Kiyoshi, Eckman, Chris, Turner, Sherry K., Fischer, Elizabeth, Younkin, Steven, Borchelt, David R., Hsiao, Karen K., Carlson, George A.

Journal:

Nature Neuroscience

Year:

1999

Language:

english

File:

PDF, 193 KB

english, 1999

22

10.1038/nn0901-887

Nilsberth, Camilla, Westlind-Danielsson, Anita, Eckman, Christopher B., Condron, Margaret M., Axelman, Karin, Forsell, Charlotte, Stenh, Charlotte, Luthman, Johan, Teplow, David B., Younkin, Steven G.

Journal:

Nature Neuroscience

Year:

2001

Language:

english

File:

PDF, 981 KB

english, 2001

23

Peptide nucleic acids targeted to the amyloid precursor protein

Beth M. McMahon, Jennifer Stewart, Abdul Fauq, Steven Younkin, Linda Younkin, Elliott Richelson

Journal:

Journal of Molecular Neuroscience

Year:

2003

Language:

english

File:

PDF, 101 KB

english, 2003

24

A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater: Management and outcomes

John R. Hornick, Fabian M. Johnston, Peter O. Simon, Morgan Younkin, Michael Chamberlin, Jonathan B. Mitchem, Riad R. Azar, David C. Linehan, Steven M. Strasberg, Steven A. Edmundowicz, William G. Haw

Journal:

Year:

2011

Language:

english

File:

PDF, 429 KB

english, 2011

25

The role of Aβ42 in Alzheimer's disease

Steven G. Younkin

Journal:

Journal of Physiology-Paris

Year:

1998

Language:

english

File:

PDF, 379 KB

english, 1998

26

Type-specific evolution of amyloid plaque and angiopathy in APPsw mice

Yasuo Harigaya, Yasushi Tomidokoro, Masaki Ikeda, Atsushi Sasaki, Takeshi Kawarabayashi, Etsuro Matsubara, Mitsuyasu Kanai, Takaomi C. Saido, Steven G. Younkin, Mikio Shoji

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 202 KB

english, 2006

27

Amyloid β Protein Starting Pyroglutamate at Position 3 Is a Major Component of the Amyloid Deposits in the Alzheimer's Disease Brain

Yasuo Harigaya, Takaomi C. Saido, Christopher B. Eckman, Cristian-Mihail Prada, Mikio Shoji, Steven G. Younkin

Journal:

Biochemical and Biophysical Research Communications

Year:

2000

Language:

english

File:

PDF, 185 KB

english, 2000

28

Co-expression of β-amyloid precursor protein (βAPP) and apolipoprotein E in cell culture: analysis of βAPP processing

Anja Leona Biere, Beth Ostaszewski, Hongwei Zhao, Susan Gillespie, Steven G. Younkin, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1995

Language:

english

File:

PDF, 576 KB

english, 1995

29

Additive Effects of PS1 and APP Mutations on Secretion of the 42-Residue Amyloid β-Protein

Martin Citron, Christopher B. Eckman, Thekla S. Diehl, Chris Corcoran, Beth L. Ostaszewski, Weiming Xia, Georges Levesque, Peter St. George Hyslop, Steven G. Younkin, Dennis J. Selkoe

Journal:

Neurobiology of Disease

Year:

1998

Language:

english

File:

PDF, 315 KB

english, 1998

30

Flemish and Dutch Mutations in Amyloid β Precursor Protein Have Different Effects on Amyloid β Secretion

Chris De Jonghe, Cynthia Zehr, Debra Yager, Cristian-Mihail Prada, Steven Younkin, Lydia Hendriks, Christine Van Broeckhoven, Christopher B. Eckman

Journal:

Neurobiology of Disease

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

31

Alterations in Cerebral Blood Flow and Glucose Utilization in Mice Overexpressing the Amyloid Precursor Protein

Kiyoshi Niwa, Ken Kazama, Steven G. Younkin, George A. Carlson, Costantino Iadecola

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

32

Cholesterol-Dependent γ-Secretase Activity in Buoyant Cholesterol-Rich Membrane Microdomains

Suzanne Wahrle, Pritam Das, Andrew C. Nyborg, Chris McLendon, Mikio Shoji, Takeshi Kawarabayashi, Linda H. Younkin, Steven G. Younkin, Todd E. Golde

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 568 KB

english, 2002

33

A Presenilin 1 Mutation Associated with Familial Frontotemporal Dementia Inhibits γ-Secretase Cleavage of APP and Notch

Zareen Amtul, Patrick A. Lewis, Sian Piper, Richard Crook, Matt Baker, Kirk Findlay, Andrew Singleton, Marion Hogg, Linda Younkin, Steven G. Younkin, John Hardy, Michael Hutton, Bradley F. Boeve, Davi

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 119 KB

english, 2002

34

Soluble derivatives of the β amyloid protein precursor of Alzheimer's disease are labeled by antisera to the β amyloid protein

Mark R. Palmert, Sandra L. Siedlak, Marcia Berman Podlisny, Barry Greenberg, Earl R. Shelton, Hardy W. Chan, Marianne Usiak, Dennis J. Selkbe, George Perry, Steven G. Younkin

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 902 KB

english, 1989

35

Secretory processing of the Alzheimer amyloid βA4 protein precursor is increased by protein phosphorylation

Susan L. Gillespie, Todd E. Golde, Steven G. Younkin

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 868 KB

english, 1992

36

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

Karen K. Hsiao, David R. Borchelt, Kristine Olson, Rosa Johannsdottir, Cheryl Kitt, Wael Yunis, Sherry Xu, Chris Eckman, Steven Younkin, Donald Price, Costantino Iadecola, H. Brent Clark, George Carls

Journal:

Year:

1995

Language:

english

File:

PDF, 3.46 MB

english, 1995

37

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

Paul H. Wen, Patrick R. Hof, Xiaoping Chen, Karen Gluck, Gregory Austin, Steven G. Younkin, Linda H. Younkin, Rita DeGasperi, Miguel A. Gama Sosa, Nikolaos K. Robakis, Vahram Haroutunian, Gregory A. E

Journal:

Experimental Neurology

Year:

2004

Language:

english

File:

PDF, 763 KB

english, 2004

38

Plasmin deficiency does not alter endogenous murine amyloid beta levels in mice

H. Michael Tucker, James Simpson, Muthoni Kihiko-Ehmann, Linda H. Younkin, Joseph P. McGillis, Steven G. Younkin, Jay L. Degen, Steven Estus

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004

39

Bosentan preserves endothelial function in mice overexpressing APP

Ahmad A. Elesber, Piero O. Bonetti, Julie E. Woodrum, Xiang-Yang Zhu, Lilach O. Lerman, Steven G. Younkin, Amir Lerman

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 137 KB

english, 2006

40

Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease

Haiyan Zhu, Jennie W. Taylor, David A. Bennett, Steven G. Younkin, Steven Estus

Journal:

Neurobiology of Aging

Year:

2008

Language:

english

File:

PDF, 67 KB

english, 2008

41

18-Month study of intravenous immunoglobulin for treatment of mild Alzheimer disease

Norman R. Relkin, Paul Szabo, Basia Adamiak, Tuna Burgut, Carmen Monthe, Richard W. Lent, Steven Younkin, Linda Younkin, Richard Schiff, Marc E. Weksler

Journal:

Neurobiology of Aging

Year:

2009

Language:

english

File:

PDF, 523 KB

english, 2009

42

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS)

Hui Shi, Olivia Belbin, Christopher Medway, Kristelle Brown, Noor Kalsheker, Minerva Carrasquillo, Petroula Proitsi, John Powell, Simon Lovestone, Alison Goate, Steven Younkin, Peter Passmore, Kevin M

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 2.02 MB

english, 2012

43

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus

Gillian Hamilton, Richard Killick, Jean-Charles Lambert, Philippe Amouyel, Minerva M. Carrasquillo, V. Shane Pankratz, Neill R. Graff-Radford, Dennis W. Dickson, Ronald C. Petersen, Steven G. Younkin,

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

44

Antisera to an amino-terminal peptide detect the amyloid protein precursor of alzheimer's disease and recognize senile plaques

Mark R. Palmert, Marcia Berman Podlisny, Dennis S. Witker, Tilman Oltersdorf, Linda H. Younkin, Dennis J. Selkoe, Steven G. Younkin

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 2.18 MB

english, 1988

45

Detection and quantitation of cellularly derived amyloid β peptides by immunoprecipitation-HPLC-MS

Nigel J Clarke, Andy J Tomlinson, Yasumasa Ohyagi, Steven Younkin, Stephen Naylor

Journal:

Year:

1998

Language:

english

File:

PDF, 205 KB

english, 1998

46

Aβ42 deposition is selectively altered in brains of Aβ1–42 immunized TG2576 mice

Pritam Das, Michael P. Murphy, Linda H. Younkin, Steven G. Younkin, Todd E. Golde

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 372 KB

english, 2000

47

Accumulation of amyloid β protein in the detergent-insoluble membrane compartment

Takeshi Kawarabayashi, Suzanne Wahrle, Linda H. Younkin, Wen-Lang Lin, Dennis W. Dickson, Steven G. Younkin

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 339 KB

english, 2000

48

Linkage analysis of plasma amyloid β protein in typical late onset Alzheimer disease (load)

Nilufer Ertekin Taner, Neill Graff-Radford, Linda H. Younkin, Michael L. Hutton, Steven G. Younkin

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

49

Role of elevated amyloid β protein in patients with typical late onset Alzheimer's disease

Steven G. Younkin, Nilufer Ertekin Taner, Tiampei Xin, Matthew Baker, Linda H. Younkin, Michael Hutton, Neill Graff-Radford

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 196 KB

english, 2000

50

The Arctic APP mutation (E693G) causes Alzheimer's disease through a novel mechanism: Increased amyloid βprotfibril formation and decreased amyloid βlevels in plasma and conditioned media

Camilla Nilsberth, Anita Westlind-Danielsson, Christopher B. Eckman, Charlotte Forsell, Karin Axelman, Johan Luthman, Steven G. Younkin, Jan Nšslund

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 185 KB

english, 2000

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